Fluoxetine (ATC: N 06 AB 03) - tymoleptyczny medicines used mainly for the treatment of depressive disorders and obsessive-kompulsyjnych. In addition, the application has been assisting in the treatment of mental ¿ar³oczno¶ci (Bulimia nervosa). It belongs to the group of SSRIs - Selective serotonin reuptake inhibitor - a selective inhibitor of serotonin uptake feedback.

Fluoxetine is used most often in the form of medicine hydrochloride. Introduced into therapeutics in 1986 (Belgium). But a well-known in the world only since 1988. Medicine is an original American pharmaceutical company Eli Lilly, which introduced him to the market under the trade name Prozac ®.

The medicine is a means of third-generation antidepressant (SSRI - Selective serotonin reuptake inhibitor). The first generation of MAO inhibitors is - now rarely used in medicine (only in severe cases, depression rozac lekoopornych), second to tricyclic antidepressants such as imipramina, amitryptylina, dezipramina, noksyptylina, doksepina and czterocykliczne antidepressants such as maprotylina, mianseryna.

The mechanism of action of pharmacological fluoksetyny (and other drugs from the SSRI group) consists of the feedback inhibition of serotonin uptake and to a lesser extent, other rozac catecholamines. Fluoxetine is metabolized in the liver to several metabolites, mainly to the active metabolite - norfluoksetyny. The effect occurs after a period of at least 2-4 weeks of treatment and maintained for 5 weeks (after a long-term use of large doses even longer) after discontinuation.


Fluoksetyny not be taken concurrently with MAO inhibitors or derivatives fenotiazyny, Sibutramine, and certain other medicines. It may also impair the ability to drive and operate machinery.

Some patients may experience side effects such as aggressive behavior, general weakness, fever, dry pozac mouth, disturbances of the gastrointestinal tract, overstrung, insomnia, headache, restlessness, excessive sweating, trembling hands, allergies, rash, decrease libido. It was also found cases of orgasm, and even a few ziewniêæ per minute, is not linked to sleepiness [3]. Side effects are generally undiminished or go as far as the continuation of fluoksetyny.

Because of the publicity in the media about the mood enhancing properties extremely Prozac was some happiness pill okrzykniêty. [Source needed]

Meta-35 clinical trials of four newer types of antidepressant drugs (fluoxetine, paroksetyna, Nefazodone, Venlafaxine was published in February 2008. Antydepresanty belonging pozac to three different groups were subjected to pharmacological analysis. Authors, it was concluded that "although the difference in the results" (between the placebo and drug antydepresyjnymi) is readily evident statistically (2%), the results reached the criteria of the National przac Institute for Clinical Health and Clinical only in the case of several patients "[4] Some articles of the scientific press in the west (" Mit prozaku "[5]," Prozak not choruj±cym helps most patients for depression [6] [7] present the discovery of a small difference in performance between the placebo and the drug by formulating the argument that antydepresyjnymi antidepressive drugs do not work.

Preparations [edit]

* Seronil - capsules / tablets in the form of hydrochloride, 10/20 mg, 30/100 pcs / ORION Pharma
* Andepin - capsules, 20 mg, 30 pcs / SYNTHESIS
* Bioxetin - tablets, 20 mg, 30 pcs / Sanofi Aventis
* Deprexetin - capsules, 20 mg, 30 pcs / ICN Polfa Rzeszow
proac * Fluoxetine przac - tablets, 10/20 mg in the form of hydrochloride, 30/90 pcs / ANPHARM
* Fluoxetine - Capsule, 20 mg in the form of hydrochloride, 30 pcs / ZF POLPHARMA
* Salipax - 20 mg in the form of hydrochloride, 10/30 pcs / MEPHA LDA
* Apo-Flox - tablets / APOTEX
* Prozac - tablets, 20 mg / ELI LILLY.

Prozac - happiness pill?
Medicine generally known as Prozac or trade name is in fact Prozak fluoxetine (Fluoxetine antidepressivum). It was established in North America in 1987 and is one of the means of third-generation antidepressant. The effect is the feedback inhibition of serotonin uptake (capture feedback - re-absorption; serotonin - a prozc substance in the central nervous system). Fluoxetine is metabolized in the liver to metabolites and biotransformation is complete.
Indications for Prozacu is primarily treatment teams depression, depression with anxiety, depression resistant to other drugs. It is used also in bulimii disease and alcohol. It can be used for: chronic exhaustion and znu¿eniu, slowed proac thinking, dwubiegunowe disease - the following consecutive periods of euphoria and despair, feelings of pleasure incapacity, natrêctwach, in cases of toxic compounds - dependence on people, excessive sensitivity to criticism and loss, excessive need for approval, fear of humiliation, as well as in the states of anxiety or low self-and nie¶mia³o¶ci.

The medicine should be used only on prescription by a doctor and is not available without a prescription. The effect occurs after a period of at least 1-4 weeks proza of treatment and persists for several weeks after discontinuation. During the application Prozaku should not be administered to the patient of other drugs with similar effect. People suffering from epilepsy, liver or kidney failure, and poisoned with ethanol should not apply Fluoksetyny. Side effects are mainly pain and dizziness, anxiety, drowsiness or insomnia, feeling of weakness, muscle tremors, nausea, vomiting, or allergic skin changes.

What makes the effects of "happiness pill"? It is the result of the adoption of the state known as hipertymia - the person in this state quickly thought, is full of enthusiasm and faith in prozc their own capabilities, firm, energetic and confident. Do not insist on the hopeless cases, and abandons them. It has reduced sensitivity, not experience a state of melancholy. Hipertymia state is not unusual, some rpozac people have spontaneously. Prozac za¿ywaj±cy words you can say about yourself "changed my life, I became more daring enough I found the girl, he founded the company and now lives as somehow man, and not as previously planned" or "After several weeks of therapy, the effects were clear: kipia³am energy , physical and mental. Not only that, I stopped thinking about death, yet I began to sing. ¶piewa³a my dog and cats. ¶piewa³a when washing dishes. A few times, even singing in the shower. "

Unfortunately, Prozac has also many negative consequences. Already in the early nineties of last century were a few worrying effects after use Prozaku. Researcher Martin Teicher of Harvard Medical School described the history of six patients, who in the course of therapy to show a strong tendency porzac prozakiem suicide. Najtragiczniejszym effect of drug use was a case of 47-year proza old Joseph Wesbeckera able to Louisville Kentucky, who in the print shop, where he worked for many years (for a while was in the release) of the Firearms postrzeli³ twenty collaborators, of which eight of them fatally. Sam had committed suicide. Treated for some time at a psychiatrist shortly before the tragedy doctor prescribed Prozac. It was noted also Prozacu use by athletes as a means dopinguj±cego or women who are seeking to lose weight with him. It was also found cases of orgasm, and even a few ziewniêæ per minute, is not linked to drowsiness. Add to that fluoxetine is added to the drug problems on menstruation.

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more about Prozac:

Trade name drug:

Prozac

International Name:

FLUOXETINI HYDROCHLORIDUM

Characters prevalence of reactions:

capsules

How does the medicine?

The medicine shows antidepressant activity by affecting the relays between cells in the nervous system.

How long before it is applied?

* It is used to treat mental illness and the depression of inhibition psychoruchowym in the course of various illnesses.
* Also found application in bulimii - by mitigating the symptoms of a strong starvation.

What are the rules you use?

* Dose and frequency with which the physician determine the drug. The medicine should be taken in the course of a meal
* It is the main meal during the przoac 1 or 3 times depending on the frequency determined by your doctor you use.
* Remember! Do not take a double dose even if they shall remember for a dose previously not accepted!

What could be undesirable consequences?

* Weakness, fever.
* Weakening of appetite, nausea, vomiting, diarrhea, feeling of dryness in the mouth.
* Headache, dizziness, insomnia, irritability, excessive sleepiness, mêczliwo¶æ, tremor, a feeling of breathlessness, anxiety.
* When these symptoms occur, and worse, contact your doctor.

The use of drug may also cause:

* Skin rash and other allergic reactions - it's the tone you use to stop and consult a doctor.
* Convulsions - to stop the use of the medicine and contact your doctor.

What should a doctor tell?

* The fact that you are allergic to the medicine. Contraindications for pregnant women and lactating mothers
* Tell your doctor if proazc you or a presumption that you may be pregnant and when karmisz child.
* Tell your doctor about other medicines that are currently taking.

Ask your doctor how to take when taking simultaneously:

* Relanium, Oxazepam, Lorazepam.
* Tricyclic antidepressants drugs (such as Imipraminê, Amitryptylinê).
* Lit.
* Do not use concurrently with MAO inhibitors (eg Jumex). Prozac can be given 14 days after completion of treatment with MAO inhibitors, and inhibitors can be given after 5 weeks after cessation of administration Prozacu.

Remember me!

* The full effect of treatment is usually achieved after 14 days of starting treatment this medicine. During this period there is a greater likelihood of suicide in people with depression. Do not handle cars and not machines
* During use, avoid driving and operating machinery in motion.
* Do not use in people under 18 years of age.

Pharmaceutical form of:
Prozac prozca (Eli Lilly and Company Ltd) 20mg capsules, 28 kaps.