Valium is the trade name of diazepam, which belongs to the group of benzodiazepine drugs (such as librium), and is best known and often prescribed sedative by doctors. Measure was introduced in 1983 and as a rule is used as a means of effectively operating in the discharge of tension and fear, and may be used in the treatment of alcohol dependence symptoms. Valium is also often used with other medicines to treat the bottom of the back pain because nerves relaxes skeletal muscles. Too high doses of valium valium or combination with alcohol or innmi means acting on the nervous system can result in a reduced or excessive irritability.
Valium and other sedatives are szerokodostepne and lead to alium drug dependence (drug addiction).


Trade name drug:


Roche Valium

International Name:

DIAZEPAMUM

Characters prevalence of reactions:

tablets

How does the medicine?

* It works on the central nervous system (brain and spinal cord).
* There is a reduction in sedation and muscle tension.
* It reduces anxiety, irritability, aggressiveness. It facilitates falling asleep.

How long before it is applied?

* It is used to treat problems with sleep (as a hypnotic), the excessive leverage and aggressive in the treatment of convulsions, tetanus, and Procured padaczkowego attack in rzucawkce Vlium pregnant.
* In premedykacji the diagnostic and surgical procedures in the conduct of postoperative patients.

What are the rules you use?

* It is used in a dose and frequency to be determined by your doctor.
* Oral, usually every 8 hours.
* In children, the different doses, depending on the age of the child.
* Please remember exactly what the doctor has determined the dosage for your child.
* Remember! Never take a double dose, even if you forget to take medication at the right time!

What could be undesirable consequences?

Vaium * Fatigue and sleepiness during the day.
* Addiction medicines.
* Dizziness.
* Blurred question.

The use of drug may also cause:

* Reduction in blood pressure.
* Difficulty in passing urine, up to a complete stop of his donation.
* Weakening of libido.
* Hepatitis.
* Difficulties with memory of events.

What should a doctor tell?

* The fact that you are allergic to the medicine.
* About that ill for glaucoma (eye disease).
Valum * To the sick to a disease called Myasthenia (nu¿liwo¶æ muscle).
* About that ill w±troby.Przeciwskazania disease for pregnant women and mothers karmi±cychNie drink alcohol
* Tell your doctor if you are or think you may be pregnant, and when karmisz breast.
* Tell your doctor about other medicines that are currently taking.

During use, avoid the adoption of:

* Alcoholic beverages.
* Medicines group barbiturates.

Ask your doctor how to take when taking simultaneously:

* Drugs which are used in the treatment of hypertensive disease.
* Amitryptylinê.
Valim * Lewodopa.
* Fenactil.

Remember me!

* Do not keep vehicles and equipment do not support mechanicznychW term you use, avoid driving and operating machinery.
* Abuse and adopting the findings of the drug without a doctor leads to addiction lekowego.

Pharmaceutical form of:
Valium Roche (Hoffmann La Roche Ltd.) tablets 5mg, 25 tabl.

Questions?:

Author: prof. Heather Ashton, DM, FRCP Emeritus Professor of Psychopharmacology and neurology direction Psychiatry, The Royal Victoria Infirmary, Queen Victoria Road, Newcastle Upon Tyne NE1 4LP, England, UK
First version: 06 August 2007. Last update: 06 August 2007.
What are the fundamental differences between the various benzodiazepines?
What are long in the body? What Valiu is their duration of action (pó³trwanie) Valium, Sobril, Xanax, Xanor, Mogadon, Rohypnol, etc..?

Answer:
Potency

He is currently a lot of medicines containing benzodiazepines. Differ in potency, which may be even stronger by 20 times. For example, 0.5 milligrams (mg) of alprazolam (Xanax) is approximately equivalent to 10 mg of diazepam (Valium). If a person takes a day alprazolam 6mg, and this dose is often prescribed in the U.S., it takes the equivalent of 120mg diazepam, which is a very high dose. The differences in the strength of these medicines are not always fully appreciated by physicians, some may not agree with the results of those tests. However, persons receiving potent benzodiazepines such as alprazolam, lorazepam (Ativan) or clonazepam (Klonopin) aVlium tend to use large quantities ralatywnie. The difference in effect of these drugs is important when the benzodiazepinu goes on under a different medication, for example, by switching to diazepam withdrawal now, has been described in the next chapter.
The rate of elimination

Benzodiazepines also differ between the speed with which they are metabolised (in the liver) and then excreted from the body in urine. For example, after half time, "half-duration" (time after which the concentration of drug in the blood drops by half after taking a single dose) for triazolam (Halcion) is only 2-5 hours, while diazepam is 20-100 hours on and its active metabolite (desmethyldiazepam) is 36-200 hours. This means that half of active diazepam is still Vlaium present in the blood for up to 200 hours of taking a single dose. Of course, after several doses throughout the day, and there is increasing concentration of drug accumulation in the cells of the body (mainly lipid, as it dissolves in fat). There are significant differences in time metabolise benzodiazepines by an individual person.
Table 1. Benzodiazepines MEDICINES AND THE LIKE 5
Benzodiazepines 5

Half-duration (h) 1
[active metabolite]

Determination of product 2

Approximate value
Oral dose (mg) 3
Alprazolam (Xanax, Xanor)
6-12

a

0.5
Bromazepam (Lexotan, Lexomil)
10-20

a

5-6
Chlordiazepoxid (Librium, Tropium)
5-30 [36-200]

a

25
Clobazam (Frisium)
12-60

a, e

20
Clonazepam (Klonopin, Klonapin, Rivotril, Liktorivil)
18-50

a, e

0.5
Clorazepat (Tranxene)
[36-200]

a

15
Diazepam (Valium, Apzepam, Stesolid)
20-100 [36-200]

a

10
Estazolam (ProSom)
10-24

h

1-2
Flunitrazepam (Rohypnol, Fluscand)
18-26 [36-200]

h

1
Flurazepam (Dalma)
[40-250]

h

15-30
Halazepam (Paxipam)
[30-100]

a

20
Ketazolam (Anxon)
2

a

15-30
Loprazolam (Dormonoct)
6-12

h

1-2
Lorazepam (Ativan, Temesta)
10-20

a

1
Lormetazepam (Noctamid)
10-12

h

1-2
Medazepam (Nobrium)
36-200

a

10
Nitrazepam (Mogadon, Apodorm)
15-38

h

10
Oxazepam (Serax, Serenid, Serepax, Sobril, Oxascand)
4-15

a

20
Prazepam (Centrax)
[36-200]

a

10-20
Quazepam (Doral)
25-100

h

20
Temazepam (Restoril, Normison, Euhypnos)
8-22

h

20
Triazole (Halcion)
2

h

0.5
Non-benzodiazepines Vailum with similar effect, 4, 5
Pó³trwanie (h) 1
[active metabolite]

Determination of product 2

Approximate value
Oral dose (mg) 3
Zaleplon (Sonata)
2

h

20
Zolpidem (Ambien, Stilnoct)
2

h

20
Zopiclone (Zimovane, Imovane, Zopiklon)
5-6

h

15

1. Half-duration: the time which is needed for one dose of drug concentration in blood had fallen to half its value. Half-duration of the active metabolite of 36-200 hours. There are big differences in time metabolise benzodiazepines by an individual person.
2. Market: All benzodiazepines act similarly, on the market are presented as anksjolytyki (a, tranquilizery), hpnotyzery, (h, sleeping pills) or antykonvulsanty (e, epileptyczne reducing seizures and convulsions).
3. Opinions on these drugs is mixed, often depending on the author. Based on the clinical experience, the results Valuim of which can vary depending on the patient.
4. These medicines are chemically differentiated from the benzodiazepines, but the effect on the body are similar.
5. All these drugs are recommended short-term (2-4 weeks maximum).

Time and effect

The rate of elimination of benzodiazepines is important in the determination of its operations. However, the apparent duration of activity is considered to be an average of half-time. In most benzodiazepines, noticeable effects appear within a few hours. However, these drugs as long as they are present in the body, kontynu³uj± effects on the body. These effects may become visible at the long-term use or may be withdrawal symptoms when dose reduction or withdrawal of Valimu treatment.